Follistatin.
Follistatin is an endogenous activin-binding glycoprotein, not a short peptide. It binds activin and myostatin, is listed under CAS 117628-82-7, has no single fixed molecular formula, and is character...
Lab Verified
Clinical Grade
PMID Cited
Mechanism of Action.
Published preclinical research has characterized the following molecular pathways and receptor interactions for Follistatin.
Myostatin (GDF-8)
Published research demonstrates Follistatin modulates targeted signaling cascades within cell tissue models.
Activin A
In cellular environments, Follistatin exhibits selective binding and corresponding pathway activation.
Clinical Literature
Research review on Follistatin molecular characterization.
Preclinical studies have characterized the molecular properties and receptor binding profiles of Follistatin in standardized assay systems.
Follistatin structure-activity relationship analysis.
Structure-activity relationship studies have examined the functional domains and binding characteristics of Follistatin in cell-free and cell-based systems.
Compound Data
| CAS Number | 117628-82-7 |
|---|---|
| Molecular Formula | N/A (recombinant protein) |
| Molecular Weight | ~37,000–40,000 Da (recombinant); ~3780 Da (synthetic truncated form) |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | −20°C · Lyophilized |
Follistatin Questions
What is Follistatin?
Follistatin is an endogenous glycoprotein that binds activin and other members of the TGF-beta superfamily, including myostatin. Evo Amino lists it under CAS 117628-82-7 and supplies it as a lyophilized research material for in vitro laboratory use only. For research purposes only. Not for human use.
Is Follistatin a peptide?
Not in the short-peptide sense. Native follistatin is a glycosylated protein of roughly three hundred amino acids, many times larger than catalog peptides such as BPC-157 or ipamorelin. That is why no single molecular formula is listed for it and why its molecular weight is given as an approximate range rather than an exact value.
How is Follistatin used in research?
In cell-based assays, follistatin serves as an activin-binding protein: it binds activin and myostatin and blocks their access to type II activin receptors, which reduces downstream SMAD2/3 signaling. Researchers use it to probe TGF-beta superfamily signaling in muscle, reproductive, and other tissue culture models.
What purity level does Evo Amino's Follistatin have?
Evo Amino supplies Follistatin at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.
How is Follistatin supplied?
Follistatin is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
Related Compounds.
HealingARA-290
$102.00C51H84N16O21 · 1257.3 g/mol
For in vitro research use only. Not for human consumption.
HealingBPC-157
$32.00C62H98N16O22 · 1419.56 g/mol
For in vitro research use only. Not for human consumption.
HealingBPC/TB500
$57.00Blend · Mixed
For in vitro research use only. Not for human consumption.