NAD+.
NAD+ (nicotinamide adenine dinucleotide) is a dinucleotide coenzyme, not a peptide. It is composed of nicotinamide and adenine connected via phosphate groups. With the molecular formula C₂₁H₂₇N₇O₁₄P₂...
Lab Verified
Clinical Grade
PMID Cited
Mechanism of Action.
Published preclinical research has characterized the following molecular pathways and receptor interactions for NAD+.
Sirtuins
NAD+ serves as a coenzyme for sirtuin deacetylases, regulating protein acetylation status in metabolic pathways.
Cellular Energy
As a redox cofactor, NAD+ cycles between oxidized and reduced states in glycolysis, TCA cycle, and oxidative phosphorylation.
Clinical Literature
Research review on NAD+ molecular characterization.
Preclinical studies have characterized the molecular properties and receptor binding profiles of NAD+ in standardized assay systems.
NAD+ structure-activity relationship analysis.
Structure-activity relationship studies have examined the functional domains and binding characteristics of NAD+ in cell-free and cell-based systems.
Compound Data
| CAS Number | 53-84-9 |
|---|---|
| Molecular Formula | C21H27N7O14P2 |
| Molecular Weight | 663.43 g/mol (anhydrous free acid) |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | −20°C · Lyophilized |
NAD+ Questions
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme made of a nicotinamide nucleotide and an adenine nucleotide joined through their phosphate groups. Evo Amino lists it with molecular formula C21H27N7O14P2, a molecular weight of 663.4 g/mol, and CAS 53-84-9. For research purposes only. Not for human use.
Is NAD+ a peptide?
No. NAD+ is a nucleotide coenzyme with no amino acids or peptide bonds. Evo Amino carries it as a research compound because it is studied in the same metabolic and cellular energy pathways as several catalog peptides, which is why its product page calls it a research compound rather than a peptide.
What role does NAD+ play in cellular research?
NAD+ is the oxidized half of the NAD+/NADH redox pair that carries electrons in glycolysis, the TCA cycle, and mitochondrial respiration. It is also the substrate that sirtuin and PARP enzymes cleave, so in vitro studies use it to probe metabolic signaling, enzyme kinetics, and cellular NAD+ pools.
What purity level does Evo Amino's NAD+ have?
Evo Amino supplies NAD+ at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.
How is NAD+ supplied?
NAD+ is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
Related Compounds.
Metabolic5-Amino-1MQ
$36.00C10H11N2 (free base) · 159.21 g/mol (free base)
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MetabolicAICAR
$57.00C9H14N4O5 · 258.23 g/mol
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MetabolicAOD9604
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For in vitro research use only. Not for human consumption.