Ipamorelin.
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue. With the molecular formula C₃₈H₄₉N₉O₅ and a molecular weight of 711.9 g/mol (CAS: 170851-70-4), Ipamorelin is derived...
Lab Verified
Clinical Grade
PMID Cited
Mechanism of Action.
Published preclinical research has characterized the following molecular pathways and receptor interactions for Ipamorelin.
GHS-R1a Receptor
Ipamorelin selectively activates the ghrelin receptor (GHS-R1a) on somatotrophs, stimulating growth hormone release without significantly affecting other pituitary hormones.
Intracellular Signaling
Receptor activation triggers phospholipase C-mediated signaling, increasing intracellular calcium and activating protein kinase C.
Clinical Literature
Research review on Ipamorelin molecular characterization.
Preclinical studies have characterized the molecular properties and receptor binding profiles of Ipamorelin in standardized assay systems.
Ipamorelin structure-activity relationship analysis.
Structure-activity relationship studies have examined the functional domains and binding characteristics of Ipamorelin in cell-free and cell-based systems.
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
Related Compounds.
GH SecretagoguesCJC no DAC
$43.00C152H252N44O42 · 3367.9 g/mol
For in vitro research use only. Not for human consumption.
GH SecretagoguesCJC/IPA
$62.00Blend · Mixed
For in vitro research use only. Not for human consumption.
GH SecretagoguesFOXO4
$196.00C228H388N86O64 · 5358.06 g/mol
For in vitro research use only. Not for human consumption.
Related Research & Analysis
Ipamorelin vs Other GH Secretagogues: CJC-1295 No DAC and Tesamorelin Research Comparison
Ipamorelin is a 711.9 g/mol pentapeptide ghrelin mimetic acting at GHS-R1a, while CJC-1295 no DAC (3367.9 g/mol) and tesamorelin (5135.9 g/mol) are GHRH-receptor analogs. A structure and receptor-class comparison of the three, with a table, covering selectivity, half-life, why the two classes are studied together, and analytical considerations. For research purposes only.
GH Secretagogue Peptides: Research Specs
Molecular comparison of GHS peptides including CJC-1295, Ipamorelin, Sermorelin, and Tesamorelin. Receptor binding sequences, pharmacokinetic modifications, and published pituitary receptor findings.