Tesamorelin.
Tesamorelin is a synthetic analog of growth hormone-releasing factor (GRF) with a trans-3-hexenoyl group attached to the tyrosine at position 1. With the molecular formula C₂₂₁H₃₆₆N₇₂O₆₇S and a molecu...
Lab Verified
Clinical Grade
PMID Cited
Mechanism of Action.
Published preclinical research has characterized the following molecular pathways and receptor interactions for Tesamorelin.
GHRH Receptor
Tesamorelin binds to GHRH receptors with enhanced affinity due to hexenoyl modification, activating Gs-protein signaling.
Clinical Literature
Research review on Tesamorelin molecular characterization.
Preclinical studies have characterized the molecular properties and receptor binding profiles of Tesamorelin in standardized assay systems.
Tesamorelin structure-activity relationship analysis.
Structure-activity relationship studies have examined the functional domains and binding characteristics of Tesamorelin in cell-free and cell-based systems.
Compound Data
| CAS Number | 218949-48-5 |
|---|---|
| Molecular Formula | C221H366N68O66S |
| Molecular Weight | 5135.89 g/mol |
| Sequence | Y(3-hexenoyl)-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
| Purity | ≥99% (HPLC verified) |
| Form | Lyophilized powder |
| Storage | −20°C · Lyophilized |
Tesamorelin Questions
What is Tesamorelin used for?
Tesamorelin is a research compound studied in laboratory settings. It has molecular formula C221H366N68O66S, a molecular weight of 5135.89 g/mol, CAS 218949-48-5. Scientific literature has explored its properties in preclinical studies. For research purposes only. Not for human use.
What purity level does Evo Amino's Tesamorelin have?
Evo Amino supplies Tesamorelin at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.
How is Tesamorelin supplied?
Tesamorelin is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.
RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
Related Compounds.
GH SecretagoguesCJC no DAC
$43.00C152H252N44O42 · 3367.9 g/mol
For in vitro research use only. Not for human consumption.
GH SecretagoguesCJC/IPA
$62.00Blend · Mixed
For in vitro research use only. Not for human consumption.
GH SecretagoguesFOXO4
$196.00C228H388N86O64 · 5358.06 g/mol
For in vitro research use only. Not for human consumption.
Related Research & Analysis
Ipamorelin vs Other GH Secretagogues: CJC-1295 No DAC and Tesamorelin Research Comparison
Ipamorelin is a 711.9 g/mol pentapeptide ghrelin mimetic acting at GHS-R1a, while CJC-1295 no DAC (3367.9 g/mol) and tesamorelin (5135.9 g/mol) are GHRH-receptor analogs. A structure and receptor-class comparison of the three, with a table, covering selectivity, half-life, why the two classes are studied together, and analytical considerations. For research purposes only.
GH Secretagogue Peptides: Research Specs
Molecular comparison of GHS peptides including CJC-1295, Ipamorelin, Sermorelin, and Tesamorelin. Receptor binding sequences, pharmacokinetic modifications, and published pituitary receptor findings.